Prim Care Companion CNS Disord 2018;20(1):17nr02229
This article is freely available to all
Article Abstract
Factitious disorder can present in multiple health care settings, with patients intentionally producing symptoms to assume the sick role. This assumption of the sick role can result in multiple hospitalizations with unnecessary diagnostic workup, as well as invasive diagnostic procedures that can lead to worrisome side effects. Differential diagnoses that should be ruled out include malingering, somatic symptom disorder, and anxiety disorders. For many providers, patients with factitious disorder can be a challenge to treat because the etiology of the disorder remains unclear. There are multiple psychological theories that attempt to explain the motivation and thought process behind the voluntary production of symptoms. Some of these theories have addressed disruptive attachments during childhood, possible intergenerational transfer of the disorder, personal identity conflicts, somatic illness as a form of masochistic activity toward oneself, and intrapsychic conflicts. Confrontation and psychotherapy with a multidisciplinary team has been proposed as a form of treatment. An understanding of the psychological factors associated with factitious disorder can help providers understand the rationale behind the patient’s presentation and aid in the formulation of a treatment plan.
CME Background
Articles are selected for credit designation based on an assessment of the educational needs of CME participants, with the purpose of providing readers with a curriculum of CME articles on a variety of topics throughout each volume. Activities are planned using a process that links identified needs with desired results.
To obtain credit, read the article, correctly answer the questions in the Posttest, and complete the Evaluation.
CME Objective
After studying this article, you should be able to:
‘ ¢ Employ an understanding of underlying psychological factors that play a role in factitious disorder when diagnosing and managing this condition
Accreditation Statement
The CME Institute of Physicians Postgraduate Press, Inc., is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Credit Designation
The CME Institute of Physicians Postgraduate Press, Inc., designates this journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Creditâ„¢. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Note: The American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Creditâ„¢ from organizations accredited by ACCME or a recognized state medical society. Physician assistants may receive a maximum of 1.0 hour of Category I credit for completing this program.
Release, Expiration, and Review Dates
This educational activity was published in February 2018 and is eligible for AMA PRA Category 1 Creditâ„¢ through February 29, 2020. The latest review of this material was January 2018.
Financial Disclosure
All individuals in a position to influence the content of this activity were asked to complete a statement regarding all relevant personal financial relationships between themselves or their spouse/partner and any commercial interest. The CME Institute has resolved any conflicts of interest that were identified. In the past year, Larry Culpepper, MD, MPH, Editor in Chief, has been a consultant for Alkermes, Jazz, Lundbeck, Merck, and Sunovion; has been a stock shareholder of M-3 Information; and has received royalties from UpToDate and Oxford University Press. No member of the CME Institute staff reported any relevant personal financial relationships. Faculty financial disclosure appears at the end of the article.
Psychological Aspects of Factitious Disorder
Mohammad Jafferany, MD, FAPAa,*; Zaira Khalid, MDa; Katherine A. McDonald, BScHb; and Amanda J. Shelley, BScHb
ABSTRACT
Factitious disorder can present in multiple health care settings, with patients intentionally producing symptoms to assume the sick role. This assumption of the sick role can result in multiple hospitalizations with unnecessary diagnostic workup, as well as invasive diagnostic procedures that can lead to worrisome side effects. Differential diagnoses that should be ruled out include malingering, somatic symptom disorder, and anxiety disorders. For many providers, patients with factitious disorder can be a challenge to treat because the etiology of the disorder remains unclear. There are multiple psychological theories that attempt to explain the motivation and thought process behind the voluntary production of symptoms. Some of these theories have addressed disruptive attachments during childhood, possible intergenerational transfer of the disorder, personal identity conflicts, somatic illness as a form of masochistic activity toward oneself, and intrapsychic conflicts. Confrontation and psychotherapy with a multidisciplinary team has been proposed as a form of treatment. An understanding of the psychological factors associated with factitious disorder can help providers understand the rationale behind the patient’s presentation and aid in the formulation of a treatment plan.
Prim Care Companion CNS Disord 2018;20(1):17nr02229
To cite: Jafferany M, Khalid Z, McDonald KA, et al. Psychological aspects of factitious disorder. Prim Care Companion CNS Disord. 2018;20(1):17nr02229.
aDepartment of Psychiatry, Central Michigan University College of Medicine, Saginaw, Michigan
bFaculty of Medicine, University of Ottawa, Ottawa, Canada
*Corresponding author: Mohammad Jafferany, MD, FAPA, Department of Psychiatry, Central Michigan University College of Medicine, 1000 Houghton Ave, Saginaw, MI 48602 ([email protected]).
Factitious disorder is currently classified in somatic symptoms and related disorders in the DSM-5. Patients with factitious, Latin for artificial, disorder present with various symptoms of disease processes that are intentionally produced to assume the role of a sick person. The symptoms are produced voluntarily and consciously with no intention of secondary gain.1 Patients assume the sick role to receive the associated care and attention from others to cope with their emotional or psychological distress.2
Attempts have been made to explain the etiology of factitious disorder via biological and psychological factors; however, the exact cause is not fully understood. Biological factors such as abnormal electroencephalogram findings, head injury, central nervous system infections, and frontotemporal cortical atrophy have been reported.1 In this article, we focus on providing a psychological explanation for the etiology of factitious disorder.
EPIDEMIOLOGY
The prevalence of factitious disorder is estimated to be 0.8%-1.0% of patients seen for a psychiatric consult.3 The prevalence of factitious disorder can be difficult to determine due to many factors including multiple providers involved in the care of these patients, patients with factitious disorder being efficient at hiding their fraudulent behavior, and lack of health care providers trained in making the diagnosis.4
It is estimated that up to 5% of all patient and physician encounters may be due to factitious production of symptoms.5 Studies2 have examined the rate of various factitious symptoms produced by patients and have reported 2.2%-9.3% of fevers to be self-induced or factitious in those presenting with fever of unknown origin, as well as 2.5% of 3,300 specimens that were submitted as renal stones to be artifacts.
Krahn et al6 studied 93 hospitalized patients with factitious disorder and reported 72% of the patients to be female, with a mean age of 30.7 years; whereas, the mean age of men was 40 years. The mean age at onset was 25 years for both sexes. Patients with factitious disorder commonly have health care-related jobs. The authors6 reported health care training was more common in women than men.
Factitious disorder is more prevalent in females, especially those with health care training, with a mean age at onset of 25 years for both sexes.
Symptoms may develop in childhood as a desire to receive comfort, attention, and protection from health care providers to compensate for a neglectful or abusive home environment.
Treatment initiation and maintenance are challenging; however, psychotherapy remains the first-line treatment for patients with factitious disorder.
CLINICAL FEATURES
The DSM-5 criteria for factitious disorder include falsification of symptoms, presenting as ill or injured, evidence of deceptive behavior, and signs and symptoms not better explained by another psychiatric diagnosis.7 The clinical presentation of these patients varies greatly from presenting with seizures or infections to headaches or kidney stones. There are multiple reports8,9 of factitious disorder in which patients have falsified laboratory tests or exaggerated symptoms. Tseng and Poullos8 described a patient who presented with Fournier’s gangrene and was found to have injected contaminated sewage water in his scrotal veins. Churchill et al9 reported a prevalence rate of 1.7% over a 5-year period of falsified HIV history and symptoms.
It is not uncommon for patients to present with psychiatric symptoms including dissociative identity disorder, bipolar disorder, depression, and psychosis. In a study10 of 100 patients sequentially admitted to an inpatient psychiatric unit, a 6% prevalence rate of factitious disorder with psychiatric symptoms was found.
Patients with factitious disorder often provide vague histories or symptoms, which are often exaggerated and do not correlate with their physical appearance. Warning signs (Table 1) for health care providers include patients seeking treatment and testing at multiple sites, inconsistent histories, and discrepancies between patient behavior, symptoms, and history.11 The physical examination may provide clues to self-inflicted injuries such as suspicious shapes or patterns of lesions or cultures that grow certain organisms.11
Click figure to enlarge
Many of these patients are very cooperative during their hospital stay and will return back to their normal lives once discharged.2 However, since assuming the sick role is important to their psychological and emotional well-being, these patients will continue the patterns of feigning symptoms and presenting to various health care providers.2
DIFFERENTIAL DIAGNOSIS
The differential diagnosis of factitious disorder includes but is not limited to somatic symptom disorder, malingering, conversion disorder, illness anxiety disorder, and anxiety disorders. Malingering is the conscious production of signs or symptoms for secondary gain, which may include drug seeking, monetary gain, and time off work. Patients with somatoform disorder have unconscious production of physical symptoms, which results in high levels of anxiety and distress in their lives. They have no intention of assuming the sick role or any other secondary gain. In conversion disorder, patients will exhibit genuine physical symptoms, which are the result of psychological distress (eg, seizures in young women at times of high stress during exam week at college).
Patients may present with high levels of anxiety or panic toward a particular symptom but do not meet criteria for factitious disorder. The main difference between any of these disorders and factitious disorder is the unconscious desire to assume the role of being sick (Table 2).11
Click figure to enlarge
PSYCHOLOGY OF FACTITIOUS DISORDER
It was previously theorized that patients with factitious disorder are aware of intentionally producing their illness but are uncertain of their motivation.12 Contrary to this previous concept of factitious disorder, it has been suggested that patients with factitious disorder are sometimes aware of why they choose to falsify a medical condition.12 However, the psychology behind these motivations remains poorly understood.
This patient group is often reluctant to participate in research studies, and, consequently, the psychology of factitious disorder is not well studied. However, a few factors have been suggested. Among factitious disorder patients, psychological reasons underlying the condition include the thrill of undergoing medical procedures,12 a need for attention or care,13 and a sense of control through the deception of health care providers.13 Other theories that have been proposed include disruption in childhood attachments, intergenerational transfer, masochistic behavior, poor self-identity, and intrapsychic defenses.14-16
Disruption in Attachments
Healthy relationships with caregivers are important for child development.14 If there are problems in these relationships, children may seek to satisfy their innate need for caregiver attention by exhibiting illness behaviors. In this way, children can satisfy their need for comfort and protection through the attention of health care providers who—through completing the duties of their jobs—act as substitute caregivers.14 These abnormal illness behaviors may extend into adolescence and adulthood. In this way, abnormal illness behaviors may affect the next generation either indirectly—if children model their own behavior after the parent with a history of factitious disorder—or directly if the parent abuses the child by forcing him or her to assume the patient role.17,18
Intergenerational Transfer
It is well established that adults who experienced abuse or neglect as children are more likely to become abusers themselves.19-22 Therefore, individuals who develop factitious disorder in childhood to cope with abuse or neglect may be more likely to become abusers as adults. Through this process of the abused becoming abusers, the offspring of adults who coped with childhood abuse through factitious disorder may be at higher risk of becoming victims of factitious disorder imposed on another (also called Munchausen syndrome by proxy).14 To simplify, the previously factitious disorder-afflicted parents may fabricate and impose illness on their children.17,18 No studies have formally examined the possibility that factitious disorder may run in families through children modeling the abnormal illness behaviors of their parents.
Personal Identity
Patients with a diagnosis of factitious disorder commonly have a history of abuse, neglect, and unstable childhood environments. Due to these factors, patients often do not develop a strong sense of self and suffer from low self-esteem. The instability of their childhood results in these patients experiencing a lack of control over their lives. Hence, patients fabricate symptoms and their medical histories, which allows them to feel a sense of control over an aspect of their lives.1 The role of an ill patient also provides these individuals an identity.15
Masochistic Attempts
Undergoing multiple invasive and possibly painful diagnostic tests, procedures, and treatment can be viewed as masochistic attempts.23 Patients may use these painful measures to punish themselves in order to cope with guilt that may exist as part of their psychiatric comorbidities or history of abuse.23
Intrapsychic Defense
A psychodynamic approach to factitious disorder is to view it as an intrapsychic defense, wherein patients feel a sense of importance when receiving close care for their somatic complaints that can counter their low self-esteem.24 When patients experience anger or aggression toward others, they mobilize somatic complaints as a pathway to obtain their attention. Once help for their somatic complaints is offered by others, these patients are able to decline it, and in this process, also reduce any intrapsychic conflict that was caused by the anger.24 Being ill is also an effective shield that protects the patient’s ego from guilt that may arise from not being able to meet expectations at work, in his or her personal life, or in any other setting.24
CLINICAL MANAGEMENT
Similar to diagnosis, treatment of factitious disorder can be difficult and usually requires a multidisciplinary team of a psychiatrist, primary care physician, therapist, social worker, and family members to help the patient develop insight and recover.1 Patients generally are not receptive to psychiatric care and will often change providers or clinical sites to prevent the pursuit of treatment. There is also a high follow-up dropout rate.25
The goal of treatment is to limit the patient’s risk of adverse reactions and health care costs of unnecessary treatment and diagnostic tests.1 Multiple case reports1 have described the benefit of psychotherapy; however, the evidence behind the use of confrontation remains unclear.
A study26 of 24 patients with factitious disorder showed only 50% of the patients accepted and pursued psychotherapy. Of those 12 patients, 2 dropped out of treatment and 10 continued therapy for 4 years. The patients are described to have “progressed favorably, with a significant, or at least marked, improvement of the symptomology and the relation capability.”26(p106)
Bolat and Yalçin25 recommend using psychoeducation followed by confrontation of the patient’s symptoms and disorder. During the psychoeducation phase, they recommend that clinicians (1) provide education regarding factitious disorder, (2) help the patient understand the distinction between factitious disorder and malingering to minimize negative reactions, (3) help the patient understand the symptoms as a request for help, and (4) describe the treatment outcome and help manage the reaction of the family to the diagnosis of factitious disorder.25 This phase is to be followed by confrontation of the patient’s symptoms. Early intervention and patient acknowledgment of deceit help prevent repetition of the cycle.
Others27 have recommended avoiding confronting the patient and using techniques such as “inexact interpretation”—the patient is informed that there is a problem; however, it is related to psychological factors. Another technique is to provide the patient with a “face-saving” treatment option to prevent any humiliation by informing the patient that the symptoms or illness may not be responsive to conventional medication treatment. Patients can be offered therapeutic techniques such as hypnosis to help with the healing of the physical and psychological distress.1
Psychopharmacologic treatment for factitious disorder and evidence for its efficacy remain lacking, as psychotherapy is considered to be first-line treatment. Treatment of any psychiatric comorbidities such as depression, anxiety, or psychosis can be beneficial for the patient. Selective serotonin reuptake inhibitors (SSRIs) may be used to treat impulsivity in patients for whom it plays a role in the production of feigned symptoms.3 There is no specific pharmacologic agent approved by the US Food and Drug Administration; however, SSRIs, antipsychotics, mood stabilizers, and antianxiety agents have been used in case reports28 with variable success.
CONCLUSION
An understanding of the underlying psychological factors that play a role in factitious disorder can assist providers in better understanding the patient’s illness. Utilization of this understanding while providing psychotherapy or using confrontation with a patient can be of great benefit in reducing the need for invasive and expensive diagnostic testing, hospital admissions, office visits, and the use of medications.
Submitted: October 6, 2017; accepted November 21, 2017.
Published online: February 22, 2018.
Disclosure of off-label usage: The authors have determined that, to the best of their knowledge, no investigational information about pharmaceutical agents that is outside US Food and Drug Administration-approved labeling has been presented in this article.
Financial disclosure: Drs Jafferany and Khalid and Mss McDonald and Shelley have no personal affiliations or financial relationships with any commercial interest to disclose relative to the article.
1. Guzman J, Correll T. Factitious disorder. Hosp Physician. 2008;11(1):2-11.
2. Savino AC, Fordtran JS. Factitious disease: clinical lessons from case studies at Baylor University Medical Center. Proc (Bayl Univ Med Cent). 2006;19(3):195-208. PubMedCrossRef
3. Sadock BJ, Sadock VA, Ruiz P. Psychosomatic medicine; factitious disorder. In: Pataki CS, Sussman N, eds. Synopsis of Psychiatry: Behavioral Science/Clinical Psychiatry. 11th ed. Philadelphia, PA: Wolters Kluwer; 2015:34-45.
4. Eaton JS Jr. Playing sick? untangling the web of Munchausen syndrome, Munchausen by proxy, malingering, and factitious disorder. Am J Psychiatry. 2006;163(2):334-335. CrossRef
5. Wallach J. Laboratory diagnosis of factitious disorders. Arch Intern Med. 1994;154(15):1690-1696. PubMedCrossRef
6. Krahn LE, Li H, O’ Connor MK. Patients who strive to be ill: factitious disorder with physical symptoms. Am J Psychiatry. 2003;160(6):1163-1168. PubMedCrossRef
7. American Psychiatric Association. Diagnostic and Statistical Manual for Mental Disorders. Fifth Edition. Washington, DC: American Psychiatric Association; 2013.
8. Tseng J, Poullos P. Factitious disorder presenting with attempted simulation of Fournier’s gangrene. J Radiol Case Rep. 2016;10(9):26-34. PubMed
9. Churchill DR, DeCock KM, Miller RF. Feigned HIV-infection/AIDS-malingering and Munchausens-syndrome. Genitourin Med. 1994;70(5):314-316. PubMed
10. Gregory R, Jindal S. Factitious disorder on an inpatient psychiatry ward. Am J Orthopsychiatry. 2006;76(1):31-36. PubMedCrossRef
11. Burnel A. Recognition and management of factitious disorder. Prescriber. 2015;26(21):37-39. CrossRef
12. Lawlor A, Kirakowski J. When the lie is the truth: grounded theory analysis of an online support group for factitious disorder. Psychiatry Res. 2014;218(1-2):209-218. PubMedCrossRef
13. Yates GP, Feldman MD. Factitious disorder: a systematic review of 455 cases in the professional literature. Gen Hosp Psychiatry. 2016;41:20-28. PubMedCrossRef
14. Kozlowska K. Abnormal illness behaviors: a developmental perspective. Lancet. 2014;383(9926):1368-1369. PubMedCrossRef
15. Willingham F. Factitious disorder. In: Fundukian LJ, Wilson J, eds. The Gale Encylopedia of Mental Health. 2nd ed. Farmington Hills, MI: Gale Group; 2012:451-455.
16. Feldman MD, Hamilton JC, Deemer HN. Factitious disorder. In: Phillips KA, ed; Oldham JM, Riba MB, series eds. Somatoform and Factitious Disorders (Review of Psychiatry). Washington, DC: American Psychiatric Publishing Inc; 2001;20(3):129-127.
17. Bass C, Halligan P. Factitious disorders and malingering: challenges for clinical assessment and management. Lancet. 2014;383(9926):1422-1432. PubMedCrossRef
18. Bass C, Glaser D. Early recognition and management of fabricated or induced illness in children. Lancet. 2014;383(9926):1412-1421. PubMedCrossRef
19. Thornberry TP, Henry KL, Smith CA, et al. Breaking the cycle of maltreatment: the role of safe, stable, and nurturing relationships. J Adolesc Health. 2013;53(suppl 4):S25-S31. PubMedCrossRef
20. Romero-Martinez A, Figueiredo B, Moya-Albiol L. Childhood history of abuse and child abuse potential: the role of parent’s gender and timing of childhood abuse. Child Abuse Negl. 2014;38(3):510-516. PubMedCrossRef
21. Plummer M, Cossins A. The cycle of abuse: when victims become offenders [published online ahead of print July 19, 2016]. Trauma Violence Abuse. PubMedCrossRef
22. Yates G, Bass C. The perpetrators of medical child abuse (Munchausen syndrome by proxy): a systematic review of 796 cases. Child Abuse Negl. 2017;72:45-53. PubMedCrossRef
23. Kellner R. Psychosomatic Syndromes and Somatic Symptoms. 1st ed. Washington, DC: American Psychiatric Press; 1991.
24. Phillips KA. Somatoform and factitious disorders. Washington DC: American Psychiatric Press, Inc; 2001.
25. Bolat N, Yalçin O. Factitious disorder presenting with stuttering in two adolescents: the importance of psychoeducation. Noro Psikiyatri Arsivi. 2017;54(1):87-89. PubMedCrossRef
26. Plassmann R. Inpatient and outpatient long-term psychotherapy of patients suffering from factitious disorders. Psychother Psychosom. 1994;62(1-2):96-107. PubMedCrossRef
28. Tomas-Aragones L. Consoli SM, Consoli SG, et al. Self-inflicted lesions in dermatology: a management and therapeutic approach. A position paper from European Society for Dermatology and Psychiatry. Acta Derm Venereol. 2017;97(2):159-172. PubMedCrossRef