Case Report: Bupropion-Induced Claustrophobia

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Sir: Although emergent anxiety can occur with bupropiontherapy (5%-6% per the package insert1), to date there are noreports of claustrophobia associated with the drug. We present acase of new-onset claustrophobia related to bupropion therapy.Case report. Mr. A, a 59-year-old man with no prior psychiatrichistory, was prescribed bupropion in May of 2005 for amajor depressive episode (DSM-IV criteria).