Neuroleptic Malignant Syndrome (NMS) is a rare but potentially life-threatening reaction to antipsychotic medications. Recognizing its symptoms and understanding its management is crucial for psychiatrists. The Journal of Clinical Psychiatry provides in-depth insights into NMS, from its pathophysiology to evidence-based treatment approaches. Our expert editors ensure that content is both clinically relevant and actionable, aiding psychiatrists in the timely diagnosis and management of this critical condition.