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As the publishers of The Journal of Clinical Psychiatry, we have the responsibility to look beyond our day-to-day operation to the broader issues and concerns that confront you, our valued readers. Now, more than at any time in recent memory, the dissemination of medical research in general, and psychiatric research in particular, is coming under fire from numerous quarters. The daily barrage of headlines has led many clinicians to question the efficacy of treatments and has even raised the specter of putting patients in harm’s way.