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The Journal of Clinical Psychiatry The Journal of Clinical Psychiatry

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  1. Département de Psychiatrie et d’Addictologie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Bichat-Claude Bernard, Paris, France
  2. Université de Paris, NeuroDiderot, Inserm, F-75019, Paris, France
  3. Corresponding author: Bénédicte Barbotin, MD, Département de Psychiatrie et d’Addictologie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Bichat-Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France ([email protected]).
  4. Centre Ressource Régional de Psychiatrie du Sujet Agé (CRRPSA), Service de Psychiatrie et d’Addictologie de l’adulte et du sujet âgé, DMU Psychiatrie et Addictologie, AP-HP, Centre-Université de Paris, Paris, France
  5. Université de Paris, Paris, France
  6. Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris, Paris, France
  7. Department of Psychiatry, New York State Psychiatric Institute/Columbia University, New York, New York
  8. Division of Epidemiology, Services, and Prevention Research, National Institute on Drug Abuse, Bethesda, Maryland
  9. Centre Ressource Régional de Psychiatrie du Sujet Agé (CRRPSA), Service de Psychiatrie et d’Addictologie de l’adulte et du sujet âgé, DMU Psychiatrie et Addictologie, AP-HP, Centre-Université de Paris, Paris, France
  10. Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris, Paris, France
  11. Département de Psychiatrie et d’Addictologie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Bichat-Claude Bernard, Paris, France
  12. Université de Paris, Paris, France
  13. GHU Paris—Psychiatry & Neurosciences, Paris, France
  14. Centre Ressource Régional de Psychiatrie du Sujet Agé (CRRPSA), Service de Psychiatrie et d’Addictologie de l’adulte et du sujet âgé, DMU Psychiatrie et Addictologie, AP-HP, Centre-Université de Paris, Paris, France
  15. Université de Paris, Paris, France
  16. Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris, Paris, France
  17. Département de Psychiatrie et d’Addictologie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Bichat-Claude Bernard, Paris, France
  18. Université de Paris, NeuroDiderot, Inserm, F-75019, Paris, France
  19. GHU Paris—Psychiatry & Neurosciences, Paris, France
  20. CNRS UPR 3212, Institute for Cellular and Integrative Neurosciences, F–67000, Strasbourg, France
  1. Center for Behavioral Health Statistics and Quality. Results from the 2017 National Survey on Drug Use and Health: Detailed Tables. SAMHSA website. https://www.samhsa.gov/data/sites/default/files/cbhsq-reports/NSDUHDetailedTabs2017/NSDUHDetailedTabs2017.htm#tab8-56A. 2017.
  2. Krishnan KRR, Delong M, Kraemer H, et al. Comorbidity of depression with other medical diseases in the elderly. Biol Psychiatry. 2002;52(6):559–588. PubMed CrossRef
  3. McIntyre RS, O’Donovan C. The human cost of not achieving full remission in depression. Can J Psychiatry. 2004;49(suppl 1):10S–16S. PubMed
  4. Geoffroy PA, Hoertel N, Etain B, et al. Insomnia and hypersomnia in major depressive episode: prevalence, sociodemographic characteristics and psychiatric comorbidity in a population-based study. J Affect Disord. 2018;226:132–141. PubMed CrossRef
  5. Fang H, Tu S, Sheng J, et al. Depression in sleep disturbance: a review on a bidirectional relationship, mechanisms and treatment. J Cell Mol Med. 2019;23(4):2324–2332. PubMed CrossRef
  6. Geoffroy PA. Clock genes and light signaling alterations in bipolar disorder: when the biological clock is off. Biol Psychiatry. 2018;84(11):775–777. PubMed CrossRef
  7. McCall WV, Blocker JN, D’Agostino R Jr, et al. Treatment of insomnia in depressed insomniacs: effects on health-related quality of life, objective and self-reported sleep, and depression. J Clin Sleep Med. 2010;6(4):322–329. PubMed CrossRef
  8. Manber R, Edinger JD, Gress JL, et al. Cognitive behavioral therapy for insomnia enhances depression outcome in patients with comorbid major depressive disorder and insomnia. Sleep. 2008;31(4):489–495. PubMed CrossRef
  9. Geoffroy PA, Tebeka S, Blanco C, et al. Shorter and longer durations of sleep are associated with an increased twelve-month prevalence of psychiatric and substance use disorders: findings from a nationally representative survey of US adults (NESARC-III). J Psychiatr Res. 2020;124:34–41. PubMed CrossRef
  10. Prather AA, Vogelzangs N, Penninx BWJH. Sleep duration, insomnia, and markers of systemic inflammation: results from the Netherlands Study of Depression and Anxiety (NESDA). J Psychiatr Res. 2015;60:95–102. PubMed CrossRef
  11. Roberts RE, Duong HT. Is there an association between short sleep duration and adolescent anxiety disorders? Sleep Med. 2017;30:82–87. PubMed CrossRef
  12. Broström A, Wahlin Å, Alehagen U, et al. Sex-specific associations between self-reported sleep duration, depression, anxiety, fatigue and daytime sleepiness in an older community-dwelling population. Scand J Caring Sci. 2018;32(1):290–298. PubMed CrossRef
  13. Zhai L, Zhang H, Zhang D. Sleep duration and depression among adults: a meta-analysis of prospective studies. Depress Anxiety. 2015;32(9):664–670. PubMed CrossRef
  14. Olfson M, Blanco C, Wall M, et al. National trends in suicide attempts among adults in the United States. JAMA Psychiatry. 2017;74(11):1095–1103. PubMed CrossRef
  15. Hedegaard H, Curtin SC, Warner M. Suicide mortality in the United States, 1999–2017. NCHS Data Brief. 2018;330:1–8. PubMed
  16. De Berardis D, Fornaro M, Valchera A, et al. Eradicating suicide at its roots: preclinical bases and clinical evidence of the efficacy of ketamine in the treatment of suicidal behaviors. Int J Mol Sci. 2018;19(10):E2888. PubMed CrossRef
  17. Wilson N, Kariisa M, Seth P, et al. Drug and opioid-involved overdose deaths—United States, 2017–2018. MMWR Morb Mortal Wkly Rep. 2020;69(11):290–297. PubMed CrossRef
  18. Oquendo MA, Volkow ND. Suicide: a silent contributor to opioid-overdose deaths. N Engl J Med. 2018;378(17):1567–1569. PubMed CrossRef
  19. Case A, Deaton A. Mortality and morbidity in the 21st century. Brookings Pap Econ Act. 2017;2017(1):397–476. PubMed CrossRef
  20. Esser MB, Sherk A, Liu Y, et al. Deaths and years of potential life lost from excessive alcohol use—United States, 2011–2015. MMWR Morb Mortal Wkly Rep. 2020;69(39):1428–1433. PubMed CrossRef
  21. Olfson M, Wall M, Liu SM, et al. Declining health-related quality of life in the US. Am J Prev Med. 2018;54(3):325–333. PubMed CrossRef
  22. Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders: an opportunity for prevention? JAMA. 1989;262(11):1479–1484. PubMed CrossRef
  23. Geoffroy PA, Oquendo MA, Courtet P, et al. Sleep complaints are associated with increased suicide risk independently of psychiatric disorders: results from a national 3-year prospective study. Mol Psychiatry. 2021;26(6):2126–2136. PubMed CrossRef
  24. Hoertel N, Franco S, Wall MM, et al. Mental disorders and risk of suicide attempt: a national prospective study. Mol Psychiatry. 2015;20(6):718–726. PubMed CrossRef
  25. Hoertel N, Blanco C, Olfson M, et al. A comprehensive model of predictors of suicide attempt in depressed individuals and effect of treatment-seeking behavior: results from a national 3-year prospective study. J Clin Psychiatry. 2018;79(5):17m11704. PubMed CrossRef
  26. Liu TZ, Xu C, Rota M, et al. Sleep duration and risk of all-cause mortality: a flexible, non-linear, meta-regression of 40 prospective cohort studies. Sleep Med Rev. 2017;32:28–36. PubMed CrossRef
  27. Cappuccio FP, D’Elia L, Strazzullo P, et al. Sleep duration and all-cause mortality: a systematic review and meta-analysis of prospective studies. Sleep. 2010;33(5):585–592. PubMed CrossRef
  28. Grant BF, Goldstein RB, Chou SP, et al. Sociodemographic and psychopathologic predictors of first incidence of DSM-IV substance use, mood and anxiety disorders: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. Mol Psychiatry. 2009;14(11):1051–1066. PubMed CrossRef
  29. Grant BF, Harford TC, Dawson DA, et al. The Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS): reliability of alcohol and drug modules in a general population sample. Drug Alcohol Depend. 1995;39(1):37–44. PubMed CrossRef
  30. Chatterji S, Saunders JB, Vrasti R, et al. Reliability of the alcohol and drug modules of the Alcohol Use Disorder and Associated Disabilities Interview Schedule–Alcohol/Drug-Revised (AUDADIS-ADR): an international comparison. Drug Alcohol Depend. 1997;47(3):171–185. PubMed CrossRef
  31. Grant BF, Dawson DA, Stinson FS, et al. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-IV (AUDADIS-IV): reliability of alcohol consumption, tobacco use, family history of depression and psychiatric diagnostic modules in a general population sample. Drug Alcohol Depend. 2003;71(1):7–16. PubMed CrossRef
  32. Koffel E, Watson D. The two-factor structure of sleep complaints and its relation to depression and anxiety. J Abnorm Psychol. 2009;118(1):183–194. PubMed CrossRef
  33. Blanco C, Wall MM, Hoertel N, et al. Psychiatric disorders and risk for multiple adverse outcomes: a national prospective study. Mol Psychiatry. 2021;26(3):907–916. PubMed CrossRef
  34. Hu L-tze, Bentler PM. Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equ Model Multidiscip J. 1999;6(1):1–55. CrossRef
  35. Amad A, Expert P, Lord LD, et al. Plastic adaptation to pathology in psychiatry: are patients with psychiatric disorders pathological experts? Neuroscientist. 2020;26(3):208–223. PubMed CrossRef
  36. Taquet M, Smith SM, Prohl AK, et al. A structural brain network of genetic vulnerability to psychiatric illness. Mol Psychiatry. 2021;26(6):2089–2100. PubMed CrossRef
  37. Cassé-Perrot C, Lanteaume L, Deguil J, et al. Neurobehavioral and cognitive changes induced by sleep deprivation in healthy volunteers. CNS Neurol Disord Drug Targets. 2016;15(7):777–801. PubMed CrossRef
  38. Berk M, Berk L. Cognition in psychiatric disorders: from models to management. Lancet Psychiatry. 2017;4(3):173–175. PubMed CrossRef
  39. Larson-Prior LJ, Ju YE, Galvin JE. Cortical-subcortical interactions in hypersomnia disorders: mechanisms underlying cognitive and behavioral aspects of the sleep-wake cycle. Front Neurol. 2014;5:165. PubMed CrossRef
  40. Tarokh L, Saletin JM, Carskadon MA. Sleep in adolescence: physiology, cognition and mental health. Neurosci Biobehav Rev. 2016;70:182–188. PubMed CrossRef
  41. Killgore WDS. Effects of sleep deprivation on cognition. Prog Brain Res. 2010;185:105–129. PubMed CrossRef
  42. Lee D. Decision making: from neuroscience to psychiatry. Neuron. 2013;78(2):233–248. PubMed CrossRef
  43. Jeste DV, Eglit GML, Palmer BW, et al. Supported decision making in serious mental illness. Psychiatry. 2018;81(1):28–40. PubMed CrossRef
  44. Robson SE, Repetto L, Gountouna VE, et al. A review of neuroeconomic gameplay in psychiatric disorders. Mol Psychiatry. 2020;25(1):67–81. PubMed CrossRef
  45. Saksvik-Lehouillier I, Saksvik SB, Dahlberg J, et al. Mild to moderate partial sleep deprivation is associated with increased impulsivity and decreased positive affect in young adults. Sleep (Basel). 2020;43(10):zsaa078. PubMed CrossRef
  46. Fineberg NA, Chamberlain SR, Goudriaan AE, et al. New developments in human neurocognition: clinical, genetic, and brain imaging correlates of impulsivity and compulsivity. CNS Spectr. 2014;19(1):69–89. PubMed CrossRef
  47. Lin SH, Lee LT, Yang YK. Serotonin and mental disorders: a concise review on molecular neuroimaging evidence. Clin Psychopharmacol Neurosci. 2014;12(3):196–202. PubMed CrossRef
  48. Freeman D, Sheaves B, Waite F, et al. Sleep disturbance and psychiatric disorders. Lancet Psychiatry. 2020;7(7):628–637. PubMed CrossRef
  49. Palagini L, Bastien CH, Marazziti D, et al. The key role of insomnia and sleep loss in the dysregulation of multiple systems involved in mood disorders: a proposed model. J Sleep Res. 2019;28(6):e12841. PubMed CrossRef
  50. Olsson CA, Byrnes GB, Lotfi-Miri M, et al. Association between 5-HTTLPR genotypes and persisting patterns of anxiety and alcohol use: results from a 10-year longitudinal study of adolescent mental health. Mol Psychiatry. 2005;10(9):868–876. PubMed CrossRef
  51. Palma-Gudiel H, Fañanás L. An integrative review of methylation at the serotonin transporter gene and its dialogue with environmental risk factors, psychopathology and 5-HTTLPR. Neurosci Biobehav Rev. 2017;72:190–209. PubMed CrossRef
  52. Krause AJ, Simon EB, Mander BA, et al. The sleep-deprived human brain. Nat Rev Neurosci. 2017;18(7):404–418. PubMed CrossRef
  53. Gujar N, Yoo SS, Hu P, et al. Sleep deprivation amplifies reactivity of brain reward networks, biasing the appraisal of positive emotional experiences. J Neurosci. 2011;31(12):4466–4474. PubMed CrossRef
  54. Wiers CE, Shumay E, Cabrera E, et al. Reduced sleep duration mediates decreases in striatal D2/D3 receptor availability in cocaine abusers. Transl Psychiatry. 2016;6(3):e752. PubMed CrossRef
  55. Volkow ND, Tomasi D, Wang GJ, et al. Evidence that sleep deprivation downregulates dopamine D2R in ventral striatum in the human brain. J Neurosci. 2012;32(19):6711–6717. PubMed CrossRef
  56. Bauer ME, Teixeira AL. Inflammation in psychiatric disorders: what comes first? Ann N Y Acad Sci. 2019;1437(1):57–67. PubMed CrossRef
  57. Yuan N, Chen Y, Xia Y, et al. Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses. Transl Psychiatry. 2019;9(1):233. PubMed CrossRef
  58. Wei ZX, Chen L, Zhang JJ, et al. Aberrations in peripheral inflammatory cytokine levels in substance use disorders: a meta-analysis of 74 studies. Addiction. 2020;115(12):2257–2267. PubMed CrossRef
  59. Irwin MR. Sleep and inflammation: partners in sickness and in health. Nat Rev Immunol. 2019;19(11):702–715. PubMed CrossRef
  60. Irwin MR, Olmstead R, Carroll JE. Sleep disturbance, sleep duration, and inflammation: a systematic review and meta-analysis of cohort studies and experimental sleep deprivation. Biol Psychiatry. 2016;80(1):40–52. PubMed CrossRef
  61. Meerlo P, Sgoifo A, Suchecki D. Restricted and disrupted sleep: effects on autonomic function, neuroendocrine stress systems and stress responsivity. Sleep Med Rev. 2008;12(3):197–210. PubMed CrossRef
  62. Brady KT, Sinha R. Co-occurring mental and substance use disorders: the neurobiological effects of chronic stress. Am J Psychiatry. 2005;162(8):1483–1493. PubMed CrossRef
  63. Sakurai T. The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness. Nat Rev Neurosci. 2007;8(3):171–181. PubMed CrossRef
  64. Sargin D. The role of the orexin system in stress response. Neuropharmacology. 2019;154:68–78. PubMed CrossRef
  65. Boutrel B, de Lecea L. Addiction and arousal: the hypocretin connection. Physiol Behav. 2008;93(4–5):947–951. PubMed CrossRef
  66. Harris GC, Wimmer M, Aston-Jones G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature. 2005;437(7058):556–559. PubMed CrossRef
  67. Johnson PL, Molosh A, Fitz SD, et al. Orexin, stress, and anxiety/panic states. Prog Brain Res. 2012;198:133–161. PubMed CrossRef
  68. James MH, Campbell EJ, Dayas CV. Role of the orexin/hypocretin system in stress-related psychiatric disorders. Curr Top Behav Neurosci. 2017;33:197–219. PubMed CrossRef
  69. Bellivier F, Geoffroy PA, Etain B, et al. Sleep- and circadian rhythm-associated pathways as therapeutic targets in bipolar disorder. Expert Opin Ther Targets. 2015;19(6):747–763. PubMed CrossRef
  70. Bunney JN, Potkin SG. Circadian abnormalities, molecular clock genes and chronobiological treatments in depression. Br Med Bull. 2008;86(1):23–32. PubMed CrossRef
  71. Geoffroy PA, Lajnef M, Bellivier F, et al. Genetic association study of circadian genes with seasonal pattern in bipolar disorders. Sci Rep. 2015;5(1):10232. PubMed CrossRef
  72. Maruani J, Anderson G, Etain B, et al. The neurobiology of adaptation to seasons: relevance and correlations in bipolar disorders. Chronobiol Int. 2018;35(10):1335–1353. PubMed CrossRef
  73. Zhang L, Ptáček LJ, Fu YH. Diversity of human clock genotypes and consequences. Prog Mol Biol Transl Sci. 2013;119:51–81. PubMed CrossRef
  74. Parekh PK, Ozburn AR, McClung CA. Circadian clock genes: effects on dopamine, reward and addiction. Alcohol. 2015;49(4):341–349. PubMed CrossRef
  75. Sarkar DK. Circadian genes, the stress axis, and alcoholism. Alcohol Res. 2012;34(3):362–366. PubMed
  76. Bloom HG, Ahmed I, Alessi CA, et al. Evidence-based recommendations for the assessment and management of sleep disorders in older persons. J Am Geriatr Soc. 2009;57(5):761–789. PubMed CrossRef
  77. Kamel NS, Gammack JK. Insomnia in the elderly: cause, approach, and treatment. Am J Med. 2006;119(6):463–469. PubMed CrossRef
  78. Foley DJ, Monjan AA, Brown SL, et al. Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep. 1995;18(6):425–432. PubMed CrossRef
  79. Li SX, Lam SP, Chan JWY, et al. Residual sleep disturbances in patients remitted from major depressive disorder: a 4-year naturalistic follow-up study. Sleep (Basel). 2012;35(8):1153–1161. PubMed CrossRef
  80. Steiger A, Pawlowski M, Kimura M. Sleep electroencephalography as a biomarker in depression. ChronoPhysiol Ther. 2015;(5):15–25. CrossRef
  81. Geoffroy PA, Scott J, Boudebesse C, et al. Sleep in patients with remitted bipolar disorders: a meta-analysis of actigraphy studies. Acta Psychiatr Scand. 2015;131(2):89–99. PubMed CrossRef
  82. Murray G, Gottlieb J, Hidalgo MP, et al. Measuring circadian function in bipolar disorders: empirical and conceptual review of physiological, actigraphic, and self-report approaches. Bipolar Disord. 2020;22(7):693–710. PubMed CrossRef
  83. Fabbri M, Beracci A, Martoni M, et al. Measuring subjective sleep quality: a review. Int J Environ Res Public Health. 2021;18(3):1082. PubMed CrossRef
  84. Boudebesse C, Geoffroy PA, Bellivier F, et al. Correlations between objective and subjective sleep and circadian markers in remitted patients with bipolar disorder. Chronobiol Int. 2014;31(5):698–704. PubMed CrossRef
  85. Geoffroy PA, Boudebesse C, Bellivier F, et al. Sleep in remitted bipolar disorder: a naturalistic case-control study using actigraphy. J Affect Disord. 2014;158:1–7. PubMed CrossRef
  86. Kaplan KA, Gruber J, Eidelman P, et al. Hypersomnia in inter-episode bipolar disorder: does it have prognostic significance? J Affect Disord. 2011;132(3):438–444. PubMed CrossRef
  87. Lichstein KL, Durrence HH, Taylor DJ, et al. Quantitative criteria for insomnia. Behav Res Ther. 2003;41(4):427–445. PubMed CrossRef
  88. Arfken CL, Joseph A, Sandhu GR, et al. The status of sleep abnormalities as a diagnostic test for major depressive disorder. J Affect Disord. 2014;156:36–45. PubMed CrossRef
  89. Lopez J, Hoffmann R, Armitage R. Reduced sleep spindle activity in early-onset and elevated risk for depression. J Am Acad Child Adolesc Psychiatry. 2010;49(9):934–943. PubMed CrossRef
  90. Pillai V, Kalmbach DA, Ciesla JA. A meta-analysis of electroencephalographic sleep in depression: evidence for genetic biomarkers. Biol Psychiatry. 2011;70(10):912–919. PubMed CrossRef
  91. Le Strat Y, Hoertel N. Correlation is no causation: gymnasium proliferation and the risk of obesity. Addiction. 2011;106(10):1871–1872. PubMed CrossRef
  92. Littlewood DL, Kyle SD, Carter LA, et al. Short sleep duration and poor sleep quality predict next-day suicidal ideation: an ecological momentary assessment study. Psychol Med. 2019;49(3):403–411. PubMed CrossRef
  93. Bertrand L, d’Ortho MP, Reynaud E, et al. Polysomnography in seasonal affective disorder: a systematic review and meta-analysis. J Affect Disord. 2021;292:405–415. PubMed CrossRef
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