Reply to Letter to the Editor "The Role of Micronutrients as Possible Mood-Stabilizing Agents"

Letter to the Editor

Sir: We are pleased to respond to the thoughtful questions raised by Dr. Pies regarding the safety of chromium and inositol in E.M.Power+, a nutrient supplement that we found effective in open trials for the treatment of bipolar disorder. This supplement contains 36 ingredients, most of which are micronutrients such as vitamins and minerals. His questions draw attention to reports of adverse effects of micronutrients.