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Letter to the Editor

Reply to “Anger in Depressive Mixed States”

Oommen K. Mammen, MD; Paul A. Pilkonis, PhD; Kadiamada N. R. Chengappa, MD; David J. Kupfer, MD

Published: November 1, 2004

Article Abstract

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Sir: In his letter, Benazzi shares data from a large data set showing the predictive value of hypomanic symptoms for anger in major depressive episodes (MDEs). Here, we address 2 issues of research and clinical significance. In Table 2 of our article,1 we presented data on the predictionof anger attacks in bipolar depression when hypomanic symptoms, depressive symptoms, and trait anger were simultaneously entered as independent variables into the regression equation.

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Volume: 65

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