Panic Attacks Associated With Topiramate

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Sir: Although topiramate is not registered in Switzerland for the treatment of bipolar disorder, it is widely prescribed for this disorder, especially in patients suffering from comorbid conditions such as weight gain.¹ We report a patient who experienced panic attacks associated with topiramate treatment. Case report. Ms. A, a 27-year-old woman with bipolar II disorder (according to the Structured Clinical Interview for DSM-IV Axis I Disorders2), had, in 2004, been stabilized for 3 months with lithium, 1200 mg/day.' ‹