Obsessive-Compulsive Disorder With Non-24-Hour Sleep-Wake Syndrome

Letter to the Editor

Sir: Previous reports have indicated that risperidone augmentation of serotonin reuptake inhibitor (SRI) treatment is effective in patients with SRI-resistant obsessive-compulsive disorder (OCD). Moreover, improvement in the quality of sleep by risperidone is increasingly reported. We present a case of a male OCD patient with non-24-hour sleep-wake syndrome who experienced a marked reduction in OCD symptoms as well as sleep-wake disturbance by the addition of risperidone to fluvoxamine.