The Emergence of Darkness Phobia in a Bipolar Patient During Quetiapine Treatment

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Sir: Worsening or emergence of anxiety symptoms induced by atypical antipsychotics has been reported in the literature, especially obsessive-compulsive symptoms.¹ Most of these cases have been described in schizophrenic patients. It is unclear how treatment with atypical antipsychotics may induce these symptoms, although a secondary serotonergic and dopaminergic dysfunction has been hypothesized.²‘ ‹’ ‹