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Functional gastrointestinal disorders such as irritable bowel syndrome (IBS) are commonly encountered in primary care, and IBS accounts for over 50% of new consultations with gastroenterologists. IBS and other related functional gastrointestinal disorders are often associated with psychiatric disorders, most frequently anxiety and depression. The evolving disease model for IBS, based on alterations in brain-gut interactions, potentially explains, at least in part, why this association is so commonly observed.