Conclusion

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Given the limitations of research to address the complexity of patient care,clinicians continue to rely heavily on consensus among experts for questions other than those on the specific efficacy of one treatment over another. Inparticular, choices of treatments, the "how to’s " of prescribing, difficult patientand treatment issues and settings, and options for nonresponders all are addressedthrough dialogue among experts. Similarly, our understanding of theneurobiology of disorders, while growing, is still incomplete and awaits cluesthat will come from examining genetic differences between those affected andthose not affected by specific disorders.