Clozapine Use in Two Full-Term Pregnancies

Letter to the Editor

Sir: The treatment of pregnant patients who have schizophrenia
is a therapeutic dilemma since all antipsychotic medications
have at least occasionally been implicated in the
development of fetal abnormalities and are classified as Pregnancy
Category C. We report the cases of two women with
treatment-resistant schizophrenia who received clozapine during
all three trimesters and delivered at term.