A Case of Unexpected and Selective Remission of a 20-Year History of Ephedrine Dependence Following Treatment With Low-Dose Aripiprazole

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Sir: Unlike cocaine and methamphetamine dependence, ephedrine dependence is not well studied; however, clinicians who treat eating disordered patients recognize it as a common phenomenon. To date, there are no medications approved by the U.S. Food and Drug Administration (FDA) for the treatment of stimulant dependence. Here we describe the case of a patient who experienced unexpected remission of a 20-year history of ephedrine dependence following treatment with low-dose aripiprazole.’ ‹