This article is available to members only. Please enjoy the abstract for free. Subscribe for instant access to the full article.
This content is restricted to subscribers
Continue Reading...
Did you know members enjoy unlimited free PDF downloads as part of their subscription? Subscribe today for instant access to this article and our entire library in your preferred format. Alternatively, you can purchase the PDF of this article individually.
Members enjoy free PDF downloads on all articles. Join today
Author Affiliations
Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, New Jersey
Department of Biostatistics and Epidemiology, School of Public Health, Rutgers University, Piscataway, New Jersey
Corresponding author: Greta A. Bushnell, PhD, MSPH, Department of Epidemiology, Rutgers School of Public Health, Center for Pharmacoepidemiology and Treatment Science, Rutgers Institute for Health, Health Care Policy and Aging Research, 112 Paterson St, New Brunswick, NJ 08901 ([email protected]).
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina
Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, New Jersey
Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, New Jersey
Department of Pharmacy Practice and Administration, Ernest Mario School of Pharmacy, Rutgers University, New Brunswick, New Jersey
Department of Epidemiology, Columbia University Mailman School of Public Health and Department of Psychiatry, Columbia University Irving Medical Center, New York, New York
References (38)
Stein MB, Goin MK, Pollack MH, et al. Practice Guideline for the Treatment of Patients with Panic Disorder. Washington, DC: American Psychiatric Association: 2009.
Stein MB, Craske MG. Treating anxiety in 2017: optimizing care to improve outcomes. JAMA. 2017;318(3):235–236. PubMedCrossRef
Generalised anxiety disorder and panic disorder in adults: management. National Institute for Health and Care Excellence. 2011. https://www.nice.org.uk/guidance/cg113
Connolly SD, Bernstein GA; Work Group on Quality Issues. Practice parameter for the assessment and treatment of children and adolescents with anxiety disorders. J Am Acad Child Adolesc Psychiatry. 2007;46(2):267–283. PubMedCrossRef
Walter HJ, Bukstein OG, Abright AR, et al. Clinical Practice Guideline for the Assessment and Treatment of Children and Adolescents With Anxiety Disorders. J Am Acad Child Adolesc Psychiatry. 2020;59(10):1107–1124. PubMedCrossRef
Dunlop BW, Davis PG. Combination treatment with benzodiazepines and SSRIs for comorbid anxiety and depression: a review. Prim Care Companion J Clin Psychiatry. 2008;10(3):222–228. PubMedCrossRef
Goddard AW, Brouette T, Almai A, et al. Early coadministration of clonazepam with sertraline for panic disorder. Arch Gen Psychiatry. 2001;58(7):681–686. PubMedCrossRef
Dobson ET, Bloch MH, Strawn JR. Efficacy and tolerability of pharmacotherapy for pediatric anxiety disorders: a network meta-analysis. J Clin Psychiatry. 2019;80(1):17r12064. PubMedCrossRef
Bushnell GA, Stürmer T, Gaynes BN, et al. Simultaneous antidepressant and benzodiazepine new use and subsequent long-term benzodiazepine use in adults with depression, United States, 2001–2014. JAMA Psychiatry. 2017;74(7):747–755. PubMedCrossRef
Furukawa TA, Streiner DL, Young LT. Antidepressant plus benzodiazepine for major depression. Cochrane Database Syst Rev. 2001;(2):CD001026. PubMed
Stein MB, Cantrell CR, Sokol MC, et al. Antidepressant adherence and medical resource use among managed care patients with anxiety disorders. Psychiatr Serv. 2006;57(5):673–680. PubMedCrossRef
Bushnell GA, Brookhart MA, Gaynes BN, et al. Examining parental medication adherence as a predictor of child medication adherence in pediatric anxiety disorders. Med Care. 2018;56(6):510–519. PubMedCrossRef
Jann M, Kennedy WK, Lopez G. Benzodiazepines: a major component in unintentional prescription drug overdoses with opioid analgesics. J Pharm Pract. 2014;27(1):5–16. PubMedCrossRef
Brunton LL, Hilal-Dandan R, Knollmann BC, eds. Goodman & Gillman’s The Pharmacological Basis of Therapeutics. 12th ed. The McGraw-Hill Companies, Inc.; 2011.
McCabe SE, West BT. Medical and nonmedical use of prescription benzodiazepine anxiolytics among US high school seniors. Addict Behav. 2014;39(5):959–964. PubMedCrossRef
Gaither JR, Shabanova V, Leventhal JM. US national trends in pediatric deaths from prescription and illicit opioids, 1999–2016. JAMA Netw Open. 2018;1(8):e186558. PubMedCrossRef
Maust DT, Lin LA, Blow FC. Benzodiazepine use and misuse among adults in the United States. Psychiatr Serv. 2019;70(2):97–106. PubMedCrossRef
Schepis TS, West BT, Teter CJ, et al. Prevalence and correlates of co-ingestion of prescription tranquilizers and other psychoactive substances by U.S. high school seniors: Results from a national survey. Addict Behav. 2016;52:8–12. PubMedCrossRef
Liu X, Chen Y, Faries DE. Adherence and persistence with branded antidepressants and generic SSRIs among managed care patients with major depressive disorder. Clinicoecon Outcomes Res. 2011;3:63–72. PubMed
Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353(5):487–497. PubMedCrossRef
Fontanella CA, Bridge JA, Marcus SC, et al. Factors associated with antidepressant adherence for Medicaid-enrolled children and adolescents. Ann Pharmacother. 2011;45(7-8):898–909. PubMedCrossRef
Paulozzi LJ, Strickler GK, Kreiner PW, et al; Centers for Disease Control and Prevention (CDC). Controlled substance prescribing patterns—prescription behavior surveillance system, eight states, 2013. MMWR Surveill Summ. 2015;64(9):1–14. PubMedCrossRef
Bandelow B, Reitt M, Röver C, et al. Efficacy of treatments for anxiety disorders: a meta-analysis. Int Clin Psychopharmacol. 2015;30(4):183–192. PubMedCrossRef
Wang Z, Whiteside SPH, Sim L, et al. Comparative effectiveness and safety of cognitive behavioral therapy and pharmacotherapy for childhood anxiety disorders: a systematic review and meta-analysis. JAMA Pediatr. 2017;171(11):1049–1056. PubMedCrossRef
Slee A, Nazareth I, Bondaronek P, et al. Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis. Lancet. 2019;393(10173):768–777. PubMedCrossRef
Brent DA, Emslie GJ, Clarke GN, et al. Predictors of spontaneous and systematically assessed suicidal adverse events in the Treatment of SSRI-Resistant Depression in Adolescents (TORDIA) study. Am J Psychiatry. 2009;166(4):418–426. PubMedCrossRef
Neutel CI, Patten SB. Risk of suicide attempts after benzodiazepine and/or antidepressant use. Ann Epidemiol. 1997;7(8):568–574. PubMedCrossRef
Cato V, Holländare F, Nordenskjöld A, et al. Association between benzodiazepines and suicide risk: a matched case-control study. BMC Psychiatry. 2019;19(1):317. PubMedCrossRef
Schulenberg JEJL, O’Malley PM, Bachman JG, et al. Monitoring the Future: National Survey Results on Drug Use, 1975–2017—College Students & Adults Ages 19–55. Volume II. Ann Arbor, MI: Institute for Social Research, The University of Michigan; 2018.
Altmann H, Stahl ST, Gebara MA, et al. Coprescribed benzodiazepines in older adults receiving antidepressants for anxiety and depressive disorders: association with treatment outcomes. J Clin Psychiatry. 2020;81(6):20m13283. PubMedCrossRef
Weisberg RB, Dyck I, Culpepper L, et al. Psychiatric treatment in primary care patients with anxiety disorders: a comparison of care received from primary care providers and psychiatrists. Am J Psychiatry. 2007;164(2):276–282. PubMedCrossRef
Dark T, Flynn HA, Rust G, et al. Epidemiology of emergency department visits for anxiety in the United States: 2009–2011. Psychiatr Serv. 2017;68(3):238–244. PubMedCrossRef
Fischer MA, Stedman MR, Lii J, et al. Primary medication non-adherence: analysis of 195,930 electronic prescriptions. J Gen Intern Med. 2010;25(4):284–290. PubMedCrossRef