Marco Pappagallo | Psychiatrist.com

REL-1017 Effects on Cognition in MDD

Original Research

REL-1017 Effects on Cognition in MDD

REL-1017 improved subjective measures of cognitive impairment, in addition to improving total MADRS and SDQ scores.

Effect of Time From Onset of MDD on Response to Esmethadone

Original Research

Effect of Time From Onset of MDD on Response to Esmethadone

Esmethadone 25 and 50 mg were more effective in reducing depression scale scores in patients who had a shorter time since their first major depressive episode.

Esmethadone in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants

Original Research

Esmethadone in Patients With Major Depressive Disorder and Inadequate Response to Standard Antidepressants

Although this trial of esmethadone did not meet its primary outcome, some secondary and post hoc outcomes were promising.